Siddharth Srivastava Lab

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Welcome to Srivastava Lab

Our lab is focused on clinical trial readiness for genetic causes of neurodevelopmental disorders (NDDs) like intellectual disability (ID) and cerebral palsy (CP), with particular emphasis on synaptopathies.

Research

We leverage a multi-modal approach encompassing: In addition to broad efforts to identify specific causes of neurodevelopmental conditions, we have focused clinical and research efforts on synaptic disorders, with specific attention to PTEN Hamartoma Tumor Syndrome, Phelan-McDermid Syndrome, and Kleefstra Syndrome.

Clinics

We strive to translate these scientific discoveries into personalized treatments and meaningful clinical practice changes. At Boston Children's Hospital, Dr. Srivastava directs the Developmental Neurogenetics Program, focused on genetic causes of neurodevelopmental disorders. The goals of the program are:
  1. Uncover genetic causes of unexplained neurodevelopmental presentations
  2. Optimize long-term neurodevelopmental outcomes
  3. Coordinate specialty care across multiple disciplines
Within this program are several specialty clinics: Dr. Srivastava also evaluates and treats patients in the Cerebral Palsy and Spasticity Program, where one of his missions is to diagnose genetic disorders presenting as cerebral palsy.